In this case also the map would have to be modified and cities quite a bit extended. These places would be in ECS what the companies we have now are in ETS2. It gets a bit more complex if you want to add more places where you can get/deliver to passengers, such as hotels, train stations, congress centers, public baths, museums and whatnot. And drivers should either come with or be upgradable to bus driver licences, which costs a lot of money of course.
Of course you also need garage slots for the busses too. Euro truck driving gives you the real truck driver experience with realistic physics and detailed interior driving featuring euro trucks with lots of customizations. And then you can set a number of hired drivers on a route. Bus driving ets2 game download for android is the latest most trending search in the united states right now. The routes should yield a bit more revenue to make up for the licence fee (like licences for routes in airline tycoon). So you either look for bus charter jobs originating in your current city going anywhere or you can buy licences for routes that you can use for your hired drivers if they are not doing random charter jobs. The latter for the purpose of keeping hired bus drivers busy. I envision a gameplay which is a mix of the type of jobs we have in ETS2 now and Airline Tycoon 1/2.
In theory i don't see much difference between driving trucks from Transinet/Krakov to EuroAcres/Berlin and driving a Bus from busterminal Krakov to busterminal Berlin, except that there are more companies where you can get/deliver truck loads from/to.